Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Sphingosine kinase 2 (Sphingosine kinase)

Seq-ID:

Q9JIA7 [Mus musculus]

Download:

Interaction Network(s):

STRING

External Source(s):

Phosida

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
D-erythro-sphingosine kinase activity, diacylglycerol kinase activity, ATP binding, protein binding, sphinganine kinase activity	membrane fraction, lysosomal membrane, cytosol	brain development, positive regulation of cell proliferation, sphinganine-1-phosphate biosynthetic process, blood vessel development, activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway, anti-apoptosis, sphingosine metabolic process, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	364	IPGHSLPRAKSELVLAPAPAP	-	17203969	HTP	0.27		-	-	0.48	-	low

Sphingosine kinase 2 (Sphingosine kinase)

Seq-ID:

Q9NRA0 [Homo sapiens]

Download:

Interaction Network(s):

STRING

External Source(s):

Phosida

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
diacylglycerol kinase activity, ATP binding, Ras GTPase binding, sphinganine kinase activity	membrane fraction, lysosomal membrane, cytosol	sphinganine-1-phosphate biosynthetic process, activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway, anti-apoptosis, cell proliferation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	389	LPATVEPASPTPAHSLPRAKS	-	18669648	HTP	0.14		-	-	0.65	-	low
S	484	PPGSPKAALHSPVSEGAPVIP	-	18669648	HTP	0.28		-	-	0.73	-	low